Into the a deeper aspect, this new chromosome step 1 diplotype could be the diplotype H1_H1, H1_H2, H1_H3, H1_H4, H1_H5, H2_H2, H2_H3, H2_H4, H2_H5, H3_H3, H3_H4, H3_H5, H4_H4, H4_H5, otherwise H5_H5, additionally the chromosome ten diplotype may include the new rs10490924 SNP inside HTRA1, where genotype is going to be GG, GT, or TT
An additional factor, deciding the identity out of specific chromosome 1 and chromosome 10 SNPs, haplotypes, or diplotypes from inside the a subject can indicate the topic is actually not getting the correct treatment for AMD. Ergo, demonstrated here are methods to own pinpointing a topic not receiving the new appropriate way to AMD comprising choosing on the topic the newest title of one or more chromosome 1 and you will chromosome ten SNPs, haplotypes, or diplotypes revealed here, in which the name of SNP, haplotype, otherwise diplotype can indicate that topic isn’t researching the fresh compatible solution to AMD.